Metronidazole resistance is a significant problem, sub-optimal treatment will increase
this risk and it may increase with poor compliance.
Treatment regimes are not without their problems e.g. GI intolerance, alcohol
interaction, pseudomembranous colitis.
Failure to take the full course will result in unsuccessful eradication.
In patients sensitive to penicillin, the regimen containing clarithromycin may be an
alternative. Other regimens may be found in the BNF (Chapter 1, Section 1.3).
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